RGC-ADOA/ref/mitocarta3.0/MitoPathways.csv

1	MitoPathway	MitoPathway Hierarchy	Genes	n_genes	L1	L2	L3
2	Mitochondrial central dogma	Mitochondrial central dogma	2810006K23Rik, Aars2, Alkbh1, Angel2, Apex1, Atad3a, Aurkaip1, Cars2, Cdk5rap1, Chchd1, Coa3, Cox14, Dap3, Dars2, Ddx28, Dhx30, Dna2, Dus2, Ears2, Elac2, Endog, Eral1, Exd2, Exog, Fars2, Fastk, Fastkd1, Fastkd2, Fastkd3, Fastkd5, Gadd45gip1, Gars, Gatb, Gatc, Gfm1, Gfm2, Grsf1, Gtpbp10, Gtpbp3, Guf1, Hars2, Hemk1, Hsd17b10, Iars2, Kars, Lactb2, Lars2, Lig3, Lrpprc, Malsu1, Mars2, Metap1d, Mettl15, Mettl17, Mettl4, Mettl5, Mettl8, Mgme1, Mief1, Mpv17l2, Mrm1, Mrm2, Mrm3, Mrpl1, Mrpl10, Mrpl11, Mrpl12, Mrpl13, Mrpl14, Mrpl15, Mrpl16, Mrpl17, Mrpl18, Mrpl19, Mrpl2, Mrpl20, Mrpl21, Mrpl22, Mrpl23, Mrpl24, Mrpl27, Mrpl28, Mrpl3, Mrpl30, Mrpl32, Mrpl33, Mrpl34, Mrpl35, Mrpl36, Mrpl37, Mrpl38, Mrpl39, Mrpl4, Mrpl40, Mrpl41, Mrpl42, Mrpl43, Mrpl44, Mrpl45, Mrpl46, Mrpl47, Mrpl48, Mrpl49, Mrpl50, Mrpl51, Mrpl52, Mrpl53, Mrpl54, Mrpl55, Mrpl57, Mrpl58, Mrpl9, Mrps10, Mrps11, Mrps12, Mrps14, Mrps15, Mrps16, Mrps17, Mrps18a, Mrps18b, Mrps18c, Mrps2, Mrps21, Mrps22, Mrps23, Mrps24, Mrps25, Mrps26, Mrps27, Mrps28, Mrps30, Mrps31, Mrps33, Mrps34, Mrps35, Mrps36, Mrps5, Mrps6, Mrps7, Mrps9, Mrrf, Mterf1a, Mterf1b, Mterf2, Mterf3, Mterf4, Mtfmt, Mtg1, Mtg2, Mtif2, Mtif3, Mto1, Mtpap, Mtres1, Mtrf1, Mtrf1l, Mutyh, Myg1, Nars2, Ngrn, Noa1, Nsun2, Nsun3, Nsun4, Ogg1, Osgepl1, Oxa1l, Pars2, Pde12, Pdf, Pif1, Pnpt1, Polb, Poldip2, Polg, Polg2, Polq, Polrmt, Ppa2, Primpol, Prorp, Ptcd1, Ptcd2, Ptcd3, Pus1, Pusl1, Qrsl1, Qtrt1, Rars2, Rbfa, Rcc1l, Recql4, Rexo2, Rmnd1, Rnaseh1, Rpusd3, Rpusd4, Sars2, Slirp, Ssbp1, Supv3l1, Taco1, Tars2, Tbrg4, Tefm, Tfam, Tfb1m, Tfb2m, Thg1l, Timm21, Top1mt, Top3a, Trit1, Trmt1, Trmt10c, Trmt2b, Trmt5, Trmu, Trnt1, Trub2, Tsfm, Tufm, Twnk, Ung, Vars2, Wars2, Yars2, Ybey, Yrdc	230	Mitochondrial central dogma
3	mtDNA maintenance	Mitochondrial central dogma > mtDNA maintenance	Apex1, Atad3a, Dna2, Endog, Exog, Lig3, Mettl4, Mgme1, Mterf1a, Mterf1b, Mterf2, Mutyh, Ogg1, Pif1, Polb, Poldip2, Polg, Polg2, Polq, Polrmt, Ppa2, Primpol, Recql4, Rnaseh1, Ssbp1, Tfam, Tfb2m, Top1mt, Top3a, Twnk, Ung	31	Mitochondrial central dogma	mtDNA maintenance
4	mtDNA replication	Mitochondrial central dogma > mtDNA maintenance > mtDNA replication	Dna2, Exog, Lig3, Mgme1, Polg, Polg2, Polrmt, Rnaseh1, Ssbp1, Tfam, Tfb2m, Top1mt, Top3a, Twnk	14	Mitochondrial central dogma	mtDNA maintenance	mtDNA replication
5	mtDNA nucleoid	Mitochondrial central dogma > mtDNA maintenance > mtDNA nucleoid	Atad3a, Mterf1a, Mterf1b, Mterf2, Poldip2, Polg, Polg2, Polrmt, Ssbp1, Tfam, Twnk	11	Mitochondrial central dogma	mtDNA maintenance	mtDNA nucleoid
6	mtDNA repair	Mitochondrial central dogma > mtDNA maintenance > mtDNA repair	Apex1, Exog, Lig3, Ogg1, Polb, Polg, Primpol, Recql4, Ung	9	Mitochondrial central dogma	mtDNA maintenance	mtDNA repair
7	mtDNA modifications	Mitochondrial central dogma > mtDNA maintenance > mtDNA modifications	Mettl4	1	Mitochondrial central dogma	mtDNA maintenance	mtDNA modifications
8	mtDNA stability and decay	Mitochondrial central dogma > mtDNA maintenance > mtDNA stability and decay	Endog, Exog, Mgme1	3	Mitochondrial central dogma	mtDNA maintenance	mtDNA stability and decay
9	mtRNA metabolism	Mitochondrial central dogma > mtRNA metabolism	Alkbh1, Angel2, Cdk5rap1, Ddx28, Dhx30, Dus2, Elac2, Endog, Eral1, Fastk, Fastkd1, Fastkd2, Fastkd3, Fastkd5, Grsf1, Gtpbp3, Hsd17b10, Lactb2, Lrpprc, Mettl15, Mettl17, Mettl5, Mettl8, Mrm1, Mrm2, Mrm3, Mrpl12, Mrpl47, Mrps7, Mrps9, Mterf1a, Mterf1b, Mto1, Mtpap, Mtres1, Myg1, Ngrn, Noa1, Nsun2, Nsun3, Nsun4, Osgepl1, Pde12, Pnpt1, Polrmt, Ppa2, Prorp, Ptcd1, Ptcd2, Pus1, Qtrt1, Rcc1l, Rexo2, Rmnd1, Rnaseh1, Rpusd3, Rpusd4, Slirp, Supv3l1, Tbrg4, Tefm, Tfam, Tfb1m, Tfb2m, Thg1l, Top1mt, Trit1, Trmt1, Trmt10c, Trmt2b, Trmt5, Trmu, Trnt1, Trub2, Ybey, Yrdc	76	Mitochondrial central dogma	mtRNA metabolism
10	Transcription	Mitochondrial central dogma > mtRNA metabolism > Transcription	Mrpl12, Mterf1a, Mterf1b, Mtres1, Polrmt, Tefm, Tfam, Tfb2m, Top1mt	9	Mitochondrial central dogma	mtRNA metabolism	Transcription
11	mtRNA granules	Mitochondrial central dogma > mtRNA metabolism > mtRNA granules	Alkbh1, Ddx28, Dhx30, Eral1, Fastk, Fastkd1, Fastkd2, Fastkd5, Grsf1, Hsd17b10, Mrm1, Mrm2, Mrpl47, Mrps7, Mrps9, Mtpap, Noa1, Prorp, Ptcd1, Ptcd2, Pus1, Rmnd1, Rpusd3, Rpusd4, Supv3l1, Tfb1m, Trmt10c, Trub2	28	Mitochondrial central dogma	mtRNA metabolism	mtRNA granules
12	Polycistronic mtRNA processing	Mitochondrial central dogma > mtRNA metabolism > Polycistronic mtRNA processing	Elac2, Fastk, Fastkd1, Fastkd2, Fastkd3, Fastkd5, Grsf1, Hsd17b10, Prorp, Ptcd2, Tbrg4, Trmt10c, Ybey	13	Mitochondrial central dogma	mtRNA metabolism	Polycistronic mtRNA processing
13	mt-tRNA modifications	Mitochondrial central dogma > mtRNA metabolism > mt-tRNA modifications	Alkbh1, Cdk5rap1, Dus2, Gtpbp3, Hsd17b10, Mto1, Nsun2, Nsun3, Osgepl1, Pus1, Qtrt1, Rpusd4, Thg1l, Trit1, Trmt1, Trmt10c, Trmt2b, Trmt5, Trmu, Trnt1, Yrdc	21	Mitochondrial central dogma	mtRNA metabolism	mt-tRNA modifications
14	mt-rRNA modifications	Mitochondrial central dogma > mtRNA metabolism > mt-rRNA modifications	Mettl15, Mettl17, Mettl5, Mrm1, Mrm2, Mrm3, Mtpap, Myg1, Ngrn, Nsun4, Rcc1l, Rpusd3, Rpusd4, Tfb1m, Trit1, Trmt2b, Trub2	17	Mitochondrial central dogma	mtRNA metabolism	mt-rRNA modifications
15	mt-mRNA modifications	Mitochondrial central dogma > mtRNA metabolism > mt-mRNA modifications	Angel2, Mtpap, Myg1, Pde12	4	Mitochondrial central dogma	mtRNA metabolism	mt-mRNA modifications
16	mtRNA stability and decay	Mitochondrial central dogma > mtRNA metabolism > mtRNA stability and decay	Endog, Fastk, Fastkd1, Fastkd2, Fastkd3, Fastkd5, Grsf1, Lactb2, Lrpprc, Mtpap, Pde12, Pnpt1, Rexo2, Rnaseh1, Slirp, Supv3l1, Tbrg4	17	Mitochondrial central dogma	mtRNA metabolism	mtRNA stability and decay
17	Translation	Mitochondrial central dogma > Translation	2810006K23Rik, Aars2, Aurkaip1, Cars2, Chchd1, Coa3, Cox14, Dap3, Dars2, Ddx28, Dhx30, Ears2, Eral1, Exd2, Fars2, Fastkd2, Gadd45gip1, Gars, Gatb, Gatc, Gfm1, Gfm2, Grsf1, Gtpbp10, Guf1, Hars2, Hemk1, Iars2, Kars, Lars2, Lrpprc, Malsu1, Mars2, Metap1d, Mettl17, Mief1, Mpv17l2, Mrm2, Mrm3, Mrpl1, Mrpl10, Mrpl11, Mrpl12, Mrpl13, Mrpl14, Mrpl15, Mrpl16, Mrpl17, Mrpl18, Mrpl19, Mrpl2, Mrpl20, Mrpl21, Mrpl22, Mrpl23, Mrpl24, Mrpl27, Mrpl28, Mrpl3, Mrpl30, Mrpl32, Mrpl33, Mrpl34, Mrpl35, Mrpl36, Mrpl37, Mrpl38, Mrpl39, Mrpl4, Mrpl40, Mrpl41, Mrpl42, Mrpl43, Mrpl44, Mrpl45, Mrpl46, Mrpl47, Mrpl48, Mrpl49, Mrpl50, Mrpl51, Mrpl52, Mrpl53, Mrpl54, Mrpl55, Mrpl57, Mrpl58, Mrpl9, Mrps10, Mrps11, Mrps12, Mrps14, Mrps15, Mrps16, Mrps17, Mrps18a, Mrps18b, Mrps18c, Mrps2, Mrps21, Mrps22, Mrps23, Mrps24, Mrps25, Mrps26, Mrps27, Mrps28, Mrps30, Mrps31, Mrps33, Mrps34, Mrps35, Mrps36, Mrps5, Mrps6, Mrps7, Mrps9, Mrrf, Mterf1a, Mterf3, Mterf4, Mtfmt, Mtg1, Mtg2, Mtif2, Mtif3, Mtres1, Mtrf1, Mtrf1l, Nars2, Ngrn, Noa1, Nsun4, Oxa1l, Pars2, Pdf, Ppa2, Ptcd3, Pusl1, Qrsl1, Rars2, Rbfa, Rmnd1, Sars2, Slirp, Taco1, Tars2, Tfb1m, Timm21, Tsfm, Tufm, Vars2, Wars2, Yars2, Ybey	155	Mitochondrial central dogma	Translation
18	Mitochondrial ribosome	Mitochondrial central dogma > Translation > Mitochondrial ribosome	Aurkaip1, Chchd1, Dap3, Gadd45gip1, Mrpl1, Mrpl10, Mrpl11, Mrpl12, Mrpl13, Mrpl14, Mrpl15, Mrpl16, Mrpl17, Mrpl18, Mrpl19, Mrpl2, Mrpl20, Mrpl21, Mrpl22, Mrpl23, Mrpl24, Mrpl27, Mrpl28, Mrpl3, Mrpl30, Mrpl32, Mrpl33, Mrpl34, Mrpl35, Mrpl36, Mrpl37, Mrpl38, Mrpl39, Mrpl4, Mrpl40, Mrpl41, Mrpl42, Mrpl43, Mrpl44, Mrpl45, Mrpl46, Mrpl47, Mrpl48, Mrpl49, Mrpl50, Mrpl51, Mrpl52, Mrpl53, Mrpl54, Mrpl55, Mrpl57, Mrpl58, Mrpl9, Mrps10, Mrps11, Mrps12, Mrps14, Mrps15, Mrps16, Mrps17, Mrps18a, Mrps18b, Mrps18c, Mrps2, Mrps21, Mrps22, Mrps23, Mrps24, Mrps25, Mrps26, Mrps27, Mrps28, Mrps30, Mrps31, Mrps33, Mrps34, Mrps35, Mrps36, Mrps5, Mrps6, Mrps7, Mrps9, Ptcd3	83	Mitochondrial central dogma	Translation	Mitochondrial ribosome
19	Mitochondrial ribosome assembly	Mitochondrial central dogma > Translation > Mitochondrial ribosome assembly	Ddx28, Dhx30, Eral1, Fastkd2, Grsf1, Gtpbp10, Malsu1, Mettl17, Mief1, Mpv17l2, Mrm2, Mrm3, Mterf1a, Mterf3, Mterf4, Mtg1, Mtg2, Ngrn, Noa1, Nsun4, Ptcd3, Rbfa, Tfb1m, Ybey	24	Mitochondrial central dogma	Translation	Mitochondrial ribosome assembly
20	Translation factors	Mitochondrial central dogma > Translation > Translation factors	2810006K23Rik, Coa3, Cox14, Gfm1, Gfm2, Hemk1, Mrpl58, Mrrf, Mtif2, Mtif3, Mtrf1, Mtrf1l, Taco1, Timm21, Tsfm, Tufm	16	Mitochondrial central dogma	Translation	Translation factors
21	mt-tRNA synthetases	Mitochondrial central dogma > Translation > mt-tRNA synthetases	Aars2, Cars2, Dars2, Ears2, Fars2, Gars, Gatb, Gatc, Hars2, Iars2, Kars, Lars2, Mars2, Nars2, Pars2, Qrsl1, Rars2, Sars2, Tars2, Vars2, Wars2, Yars2	22	Mitochondrial central dogma	Translation	mt-tRNA synthetases
22	fMet processing	Mitochondrial central dogma > Translation > fMet processing	Metap1d, Mtfmt, Pdf	3	Mitochondrial central dogma	Translation	fMet processing
23	Protein import, sorting and homeostasis	Protein import, sorting and homeostasis	Afg1l, Afg3l1, Afg3l2, Agk, Aifm1, Atad1, Atp23, Casp3, Casp8, Casp9, Chchd4, Clpb, Clpp, Clpx, Dnaja3, Dnajc11, Dnajc15, Dnajc19, Dnajc4, Dnlz, Fkbp10, Gfer, Grpel1, Grpel2, Hspd1, Hspe1, Htra2, Ide, Immp1l, Immp2l, Lactb, Lap3, Lonp1, Maip1, Metap1d, Mipep, Mtx1, Mtx2, Mul1, Nln, Nrd1, Oma1, Oxa1l, Pam16, Park7, Parl, Pdf, Phb, Phb2, Pitrm1, Pmpca, Pmpcb, Prss35, Romo1, Samm50, Spg7, Stoml2, Timm10, Timm10b, Timm13, Timm17a, Timm17b, Timm21, Timm22, Timm23, Timm29, Timm44, Timm50, Timm8a1, Timm8a2, Timm8b, Timm9, Tomm20, Tomm20l, Tomm22, Tomm34, Tomm40, Tomm40l, Tomm5, Tomm6, Tomm7, Tomm70a, Trap1, Uqcrc1, Uqcrc2, Usp30, Xpnpep3, Yme1l1	88	Protein import, sorting and homeostasis
24	Protein import and sorting	Protein import, sorting and homeostasis > Protein import and sorting	Agk, Aifm1, Chchd4, Dnajc11, Dnajc15, Dnajc19, Gfer, Grpel1, Grpel2, Immp1l, Immp2l, Mipep, Mtx1, Mtx2, Nrd1, Oxa1l, Pam16, Pmpca, Pmpcb, Romo1, Samm50, Timm10, Timm10b, Timm13, Timm17a, Timm17b, Timm21, Timm22, Timm23, Timm29, Timm44, Timm50, Timm8a1, Timm8a2, Timm8b, Timm9, Tomm20, Tomm20l, Tomm22, Tomm34, Tomm40, Tomm40l, Tomm5, Tomm6, Tomm7, Tomm70a, Uqcrc1, Uqcrc2, Xpnpep3	49	Protein import, sorting and homeostasis	Protein import and sorting
25	TOM	Protein import, sorting and homeostasis > Protein import and sorting > TOM	Tomm20, Tomm22, Tomm34, Tomm40, Tomm40l, Tomm5, Tomm6, Tomm7, Tomm70a	9	Protein import, sorting and homeostasis	Protein import and sorting	TOM
26	SAM	Protein import, sorting and homeostasis > Protein import and sorting > SAM	Mtx1, Mtx2, Samm50	3	Protein import, sorting and homeostasis	Protein import and sorting	SAM
27	MIA40	Protein import, sorting and homeostasis > Protein import and sorting > MIA40	Aifm1, Chchd4, Gfer	3	Protein import, sorting and homeostasis	Protein import and sorting	MIA40
28	TIM22 carrier pathway	Protein import, sorting and homeostasis > Protein import and sorting > TIM22 carrier pathway	Agk, Timm22, Timm29	3	Protein import, sorting and homeostasis	Protein import and sorting	TIM22 carrier pathway
29	TIM23 presequence pathway	Protein import, sorting and homeostasis > Protein import and sorting > TIM23 presequence pathway	Romo1, Timm17a, Timm17b, Timm21, Timm23, Timm50	6	Protein import, sorting and homeostasis	Protein import and sorting	TIM23 presequence pathway
30	Import motor	Protein import, sorting and homeostasis > Protein import and sorting > Import motor	Dnajc15, Dnajc19, Grpel1, Grpel2, Pam16, Timm44	6	Protein import, sorting and homeostasis	Protein import and sorting	Import motor
31	OXA	Protein import, sorting and homeostasis > Protein import and sorting > OXA	Oxa1l	1	Protein import, sorting and homeostasis	Protein import and sorting	OXA
32	Preprotein cleavage	Protein import, sorting and homeostasis > Protein import and sorting > Preprotein cleavage	Immp1l, Immp2l, Mipep, Pmpca, Pmpcb, Uqcrc1, Uqcrc2, Xpnpep3	8	Protein import, sorting and homeostasis	Protein import and sorting	Preprotein cleavage
33	Protein homeostasis	Protein import, sorting and homeostasis > Protein homeostasis	Afg1l, Afg3l1, Afg3l2, Atad1, Atp23, Casp3, Casp8, Casp9, Clpb, Clpp, Clpx, Dnaja3, Dnajc4, Dnlz, Fkbp10, Hspd1, Hspe1, Htra2, Ide, Immp1l, Immp2l, Lactb, Lap3, Lonp1, Maip1, Metap1d, Mipep, Mul1, Nln, Nrd1, Oma1, Park7, Parl, Pdf, Phb, Phb2, Pitrm1, Pmpca, Pmpcb, Prss35, Spg7, Stoml2, Timm10, Timm10b, Timm13, Timm8a1, Timm8a2, Timm8b, Timm9, Trap1, Usp30, Xpnpep3, Yme1l1	53	Protein import, sorting and homeostasis	Protein homeostasis
34	Proteases	Protein import, sorting and homeostasis > Protein homeostasis > Proteases	Afg1l, Afg3l1, Afg3l2, Atad1, Atp23, Casp3, Casp9, Clpb, Clpp, Clpx, Htra2, Ide, Immp1l, Immp2l, Lactb, Lap3, Lonp1, Metap1d, Mipep, Nln, Oma1, Parl, Pitrm1, Pmpca, Pmpcb, Spg7, Usp30, Xpnpep3, Yme1l1	29	Protein import, sorting and homeostasis	Protein homeostasis	Proteases
35	Chaperones	Protein import, sorting and homeostasis > Protein homeostasis > Chaperones	Dnaja3, Dnlz, Fkbp10, Hspd1, Hspe1, Maip1, Nrd1, Phb, Phb2, Timm10, Timm10b, Timm13, Timm8a1, Timm8a2, Timm8b, Timm9, Trap1	17	Protein import, sorting and homeostasis	Protein homeostasis	Chaperones
36	OXPHOS	OXPHOS	Acad9, Aifm1, Atp5a1, Atp5b, Atp5c1, Atp5d, Atp5e, Atp5g1, Atp5g2, Atp5g3, Atp5h, Atp5j, Atp5j2, Atp5k, Atp5l, Atp5md, Atp5mpl, Atp5o, Atp5pb, Atpaf1, Atpaf2, Atpif1, Atpsckmt, Bcs1l, Cep89, Cmc1, Cmc2, Coa3, Coa4, Coa5, Coa6, Coa7, Coa8, Cox10, Cox11, Cox14, Cox15, Cox16, Cox17, Cox18, Cox19, Cox20, Cox4i1, Cox4i2, Cox5a, Cox5b, Cox6a1, Cox6a2, Cox6b1, Cox6b2, Cox6c, Cox7a1, Cox7a2, Cox7a2l, Cox7b, Cox7c, Cox8a, Cox8b, Cox8c, Cyc1, Cycs, Cyct, Dmac1, Dmac2, Dmac2l, Ecsit, Fmc1, Foxred1, Hccs, Higd1a, Higd2a, Lyrm2, Lyrm7, mt-Atp6, mt-Atp8, mt-Co1, mt-Co2, mt-Co3, mt-Cytb, mt-Nd1, mt-Nd2, mt-Nd3, mt-Nd4, mt-Nd4l, mt-Nd5, mt-Nd6, Ndufa1, Ndufa10, Ndufa11, Ndufa12, Ndufa13, Ndufa2, Ndufa3, Ndufa4, Ndufa5, Ndufa6, Ndufa7, Ndufa8, Ndufa9, Ndufab1, Ndufaf1, Ndufaf2, Ndufaf3, Ndufaf4, Ndufaf5, Ndufaf6, Ndufaf7, Ndufaf8, Ndufb10, Ndufb11, Ndufb2, Ndufb3, Ndufb4, Ndufb5, Ndufb6, Ndufb7, Ndufb8, Ndufb9, Ndufc1, Ndufc2, Ndufs1, Ndufs2, Ndufs3, Ndufs4, Ndufs5, Ndufs6, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Ndufv3, Nubpl, Pet100, Pet117, Pnkd, Rab5if, Sco1, Sco2, Sdha, Sdhaf1, Sdhaf2, Sdhaf3, Sdhaf4, Sdhb, Sdhc, Sdhd, Smim20, Surf1, Taco1, Timm21, Timmdc1, Tmem126a, Tmem126b, Tmem177, Tmem186, Tmem70, Ttc19, Uqcc1, Uqcc2, Uqcc3, Uqcr10, Uqcr11, Uqcrb, Uqcrc1, Uqcrc2, Uqcrfs1, Uqcrh, Uqcrq	168	OXPHOS
37	OXPHOS subunits	OXPHOS > OXPHOS subunits	Atp5a1, Atp5b, Atp5c1, Atp5d, Atp5e, Atp5g1, Atp5g2, Atp5g3, Atp5h, Atp5j, Atp5j2, Atp5k, Atp5l, Atp5md, Atp5mpl, Atp5o, Atp5pb, Atpif1, Cox4i1, Cox4i2, Cox5a, Cox5b, Cox6a1, Cox6a2, Cox6b1, Cox6b2, Cox6c, Cox7a1, Cox7a2, Cox7a2l, Cox7b, Cox7c, Cox8a, Cox8b, Cox8c, Cyc1, Cycs, Cyct, Dmac2l, Hccs, mt-Atp6, mt-Atp8, mt-Co1, mt-Co2, mt-Co3, mt-Cytb, mt-Nd1, mt-Nd2, mt-Nd3, mt-Nd4, mt-Nd4l, mt-Nd5, mt-Nd6, Ndufa1, Ndufa10, Ndufa11, Ndufa12, Ndufa13, Ndufa2, Ndufa3, Ndufa4, Ndufa5, Ndufa6, Ndufa7, Ndufa8, Ndufa9, Ndufab1, Ndufb10, Ndufb11, Ndufb2, Ndufb3, Ndufb4, Ndufb5, Ndufb6, Ndufb7, Ndufb8, Ndufb9, Ndufc1, Ndufc2, Ndufs1, Ndufs2, Ndufs3, Ndufs4, Ndufs5, Ndufs6, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Ndufv3, Sdha, Sdhb, Sdhc, Sdhd, Uqcr10, Uqcr11, Uqcrb, Uqcrc1, Uqcrc2, Uqcrfs1, Uqcrh, Uqcrq	102	OXPHOS	OXPHOS subunits
38	OXPHOS assembly factors	OXPHOS > OXPHOS assembly factors	Acad9, Aifm1, Atpaf1, Atpaf2, Atpsckmt, Bcs1l, Cep89, Cmc1, Cmc2, Coa3, Coa4, Coa5, Coa6, Coa7, Coa8, Cox10, Cox11, Cox14, Cox15, Cox16, Cox17, Cox18, Cox19, Cox20, Cox7a2l, Dmac1, Dmac2, Ecsit, Fmc1, Foxred1, Higd1a, Higd2a, Lyrm2, Lyrm7, Ndufaf1, Ndufaf2, Ndufaf3, Ndufaf4, Ndufaf5, Ndufaf6, Ndufaf7, Ndufaf8, Nubpl, Pet100, Pet117, Pnkd, Rab5if, Sco1, Sco2, Sdhaf1, Sdhaf2, Sdhaf3, Sdhaf4, Smim20, Surf1, Taco1, Timm21, Timmdc1, Tmem126a, Tmem126b, Tmem177, Tmem186, Tmem70, Ttc19, Uqcc1, Uqcc2, Uqcc3	67	OXPHOS	OXPHOS assembly factors
39	Complex I	OXPHOS > Complex I	Acad9, Aifm1, Dmac1, Dmac2, Ecsit, Foxred1, Lyrm2, mt-Nd1, mt-Nd2, mt-Nd3, mt-Nd4, mt-Nd4l, mt-Nd5, mt-Nd6, Ndufa1, Ndufa10, Ndufa11, Ndufa12, Ndufa13, Ndufa2, Ndufa3, Ndufa5, Ndufa6, Ndufa7, Ndufa8, Ndufa9, Ndufab1, Ndufaf1, Ndufaf2, Ndufaf3, Ndufaf4, Ndufaf5, Ndufaf6, Ndufaf7, Ndufaf8, Ndufb10, Ndufb11, Ndufb2, Ndufb3, Ndufb4, Ndufb5, Ndufb6, Ndufb7, Ndufb8, Ndufb9, Ndufc1, Ndufc2, Ndufs1, Ndufs2, Ndufs3, Ndufs4, Ndufs5, Ndufs6, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Ndufv3, Nubpl, Timmdc1, Tmem126a, Tmem126b, Tmem186, Tmem70	64	OXPHOS	Complex I
40	CI subunits	OXPHOS > Complex I > CI subunits	mt-Nd1, mt-Nd2, mt-Nd3, mt-Nd4, mt-Nd4l, mt-Nd5, mt-Nd6, Ndufa1, Ndufa10, Ndufa11, Ndufa12, Ndufa13, Ndufa2, Ndufa3, Ndufa5, Ndufa6, Ndufa7, Ndufa8, Ndufa9, Ndufab1, Ndufb10, Ndufb11, Ndufb2, Ndufb3, Ndufb4, Ndufb5, Ndufb6, Ndufb7, Ndufb8, Ndufb9, Ndufc1, Ndufc2, Ndufs1, Ndufs2, Ndufs3, Ndufs4, Ndufs5, Ndufs6, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Ndufv3	43	OXPHOS	Complex I	CI subunits
41	CI assembly factors	OXPHOS > Complex I > CI assembly factors	Acad9, Aifm1, Dmac1, Dmac2, Ecsit, Foxred1, Lyrm2, Ndufaf1, Ndufaf2, Ndufaf3, Ndufaf4, Ndufaf5, Ndufaf6, Ndufaf7, Ndufaf8, Nubpl, Timmdc1, Tmem126a, Tmem126b, Tmem186, Tmem70	21	OXPHOS	Complex I	CI assembly factors
42	Complex II	OXPHOS > Complex II	Sdha, Sdhaf1, Sdhaf2, Sdhaf3, Sdhaf4, Sdhb, Sdhc, Sdhd	8	OXPHOS	Complex II
43	CII subunits	OXPHOS > Complex II > CII subunits	Sdha, Sdhb, Sdhc, Sdhd	4	OXPHOS	Complex II	CII subunits
44	CII assembly factors	OXPHOS > Complex II > CII assembly factors	Sdhaf1, Sdhaf2, Sdhaf3, Sdhaf4	4	OXPHOS	Complex II	CII assembly factors
45	Complex III	OXPHOS > Complex III	Bcs1l, Cyc1, Lyrm7, mt-Cytb, Ttc19, Uqcc1, Uqcc2, Uqcc3, Uqcr10, Uqcr11, Uqcrb, Uqcrc1, Uqcrc2, Uqcrfs1, Uqcrh, Uqcrq	16	OXPHOS	Complex III
46	CIII subunits	OXPHOS > Complex III > CIII subunits	Cyc1, mt-Cytb, Uqcr10, Uqcr11, Uqcrb, Uqcrc1, Uqcrc2, Uqcrfs1, Uqcrh, Uqcrq	10	OXPHOS	Complex III	CIII subunits
47	CIII assembly factors	OXPHOS > Complex III > CIII assembly factors	Bcs1l, Lyrm7, Ttc19, Uqcc1, Uqcc2, Uqcc3	6	OXPHOS	Complex III	CIII assembly factors
48	Complex IV	OXPHOS > Complex IV	Cep89, Cmc1, Cmc2, Coa3, Coa4, Coa5, Coa6, Coa7, Coa8, Cox10, Cox11, Cox14, Cox15, Cox16, Cox17, Cox18, Cox19, Cox20, Cox4i1, Cox4i2, Cox5a, Cox5b, Cox6a1, Cox6a2, Cox6b1, Cox6b2, Cox6c, Cox7a1, Cox7a2, Cox7a2l, Cox7b, Cox7c, Cox8a, Cox8b, Cox8c, Higd1a, mt-Co1, mt-Co2, mt-Co3, Ndufa4, Pet100, Pet117, Pnkd, Sco1, Sco2, Smim20, Surf1, Taco1, Timm21, Tmem177	50	OXPHOS	Complex IV
49	CIV subunits	OXPHOS > Complex IV > CIV subunits	Cox4i1, Cox4i2, Cox5a, Cox5b, Cox6a1, Cox6a2, Cox6b1, Cox6b2, Cox6c, Cox7a1, Cox7a2, Cox7a2l, Cox7b, Cox7c, Cox8a, Cox8b, Cox8c, mt-Co1, mt-Co2, mt-Co3, Ndufa4	21	OXPHOS	Complex IV	CIV subunits
50	CIV assembly factors	OXPHOS > Complex IV > CIV assembly factors	Cep89, Cmc1, Cmc2, Coa3, Coa4, Coa5, Coa6, Coa7, Coa8, Cox10, Cox11, Cox14, Cox15, Cox16, Cox17, Cox18, Cox19, Cox20, Higd1a, Pet100, Pet117, Pnkd, Sco1, Sco2, Smim20, Surf1, Taco1, Timm21, Tmem177	29	OXPHOS	Complex IV	CIV assembly factors
51	Complex V	OXPHOS > Complex V	Atp5a1, Atp5b, Atp5c1, Atp5d, Atp5e, Atp5g1, Atp5g2, Atp5g3, Atp5h, Atp5j, Atp5j2, Atp5k, Atp5l, Atp5md, Atp5mpl, Atp5o, Atp5pb, Atpaf1, Atpaf2, Atpif1, Atpsckmt, Dmac2l, Fmc1, mt-Atp6, mt-Atp8, Tmem70	26	OXPHOS	Complex V
52	CV subunits	OXPHOS > Complex V > CV subunits	Atp5a1, Atp5b, Atp5c1, Atp5d, Atp5e, Atp5g1, Atp5g2, Atp5g3, Atp5h, Atp5j, Atp5j2, Atp5k, Atp5l, Atp5md, Atp5mpl, Atp5o, Atp5pb, Atpif1, Dmac2l, mt-Atp6, mt-Atp8	21	OXPHOS	Complex V	CV subunits
53	CV assembly factors	OXPHOS > Complex V > CV assembly factors	Atpaf1, Atpaf2, Atpsckmt, Fmc1, Tmem70	5	OXPHOS	Complex V	CV assembly factors
54	Respirasome assembly	OXPHOS > Respirasome assembly	Cox7a2l, Higd1a, Higd2a, Rab5if	4	OXPHOS	Respirasome assembly
55	Cytochrome C	OXPHOS > Cytochrome C	Cycs, Cyct, Hccs	3	OXPHOS	Cytochrome C
56	Metabolism	Metabolism	Aadat, Aass, Abat, Abcb10, Abcb6, Abcb7, Abhd10, Abhd11, Acaa1a, Acaa1b, Acaa2, Acaca, Acacb, Acad10, Acad11, Acad12, Acad8, Acadl, Acadm, Acads, Acadsb, Acadvl, Acat1, Acly, Aco2, Acod1, Acot10, Acot11, Acot13, Acot2, Acot7, Acot9, Acp6, Acsf2, Acsf3, Acsl1, Acsl6, Acsm1, Acsm2, Acsm3, Acsm4, Acsm5, Acss1, Acss3, Adhfe1, Agk, Agmat, Agpat4, Agpat5, Agxt, Agxt2, Aifm2, Aifm3, Ak2, Ak3, Ak4, Akr1b10, Akr1b7, Akr7a5, Alas1, Alas2, Aldh18a1, Aldh1b1, Aldh1l1, Aldh1l2, Aldh2, Aldh3a2, Aldh4a1, Aldh5a1, Aldh6a1, Aldh7a1, Aldh9a1, Amacr, Amt, Antkmt, Arg2, Auh, Bcat2, Bckdha, Bckdhb, Bckdk, Bco2, Bdh1, Bola1, Bola3, Bphl, Car5a, Car5b, Cat, Cbr2, Cbr3, Cbr4, Chchd7, Chdh, Chpt1, Cisd1, Cisd3, Ckmt1, Ckmt2, Clybl, Cmpk2, Coasy, Comt, Coq10a, Coq10b, Coq2, Coq3, Coq4, Coq5, Coq6, Coq7, Coq8a, Coq8b, Coq9, Cox10, Cox11, Cox15, Cox17, Cox19, Cpox, Cps1, Cpt1a, Cpt1b, Cpt1c, Cpt2, Crat, Crls1, Crot, Cs, Cyb5b, Cyb5r3, Cyc1, Cycs, Cyct, Cyp11a1, Cyp11b1, Cyp11b2, Cyp24a1, Cyp27a1, Cyp27b1, D2hgdh, Dbi, Dbt, Dcxr, Decr1, Dglucy, Dguok, Dhodh, Dhrs1, Dhrs2, Dhrs4, Dhtkd1, Dlat, Dld, Dlst, Dmgdh, Dna2, Dut, Ech1, Echdc1, Echs1, Eci1, Eci2, Ehhadh, Ephx2, Etfa, Etfb, Etfbkmt, Etfdh, Etfrf1, Ethe1, Fabp1, Fahd1, Fam210b, Fasn, Fdps, Fdx1, Fdx2, Fdxr, Fech, Fh1, Fhit, Flad1, Fpgs, Fth1, Ftmt, Fxn, Gatm, Gcat, Gcdh, Gcsh, Gldc, Glrx2, Glrx5, Gls, Gls2, Glud1, Glyat, Glyctk, Gm4952, Gm4984, Got2, Gpam, Gpat2, Gpd2, Gpt2, Gpx1, Gpx4, Grhpr, Grpel1, Grpel2, Gsr, Gstk1, Gstz1, Gtpbp3, Guk1, H2-Ke6, Hadh, Hadha, Hadhb, Hagh, Hao2, Hccs, Hibadh, Hibch, Hint1, Hint2, Hmgcl, Hmgcs2, Hoga1, Hscb, Hsd17b10, Hsd17b4, Hspa9, Htd2, Iba57, Idh2, Idh3a, Idh3b, Idh3g, Idi1, Isca1, Isca2, Iscu, Ivd, Kmo, Kyat3, L2hgdh, Lactb, Ldhal6b, Ldhb, Ldhd, Lias, Lipt1, Lipt2, Lypla1, Lyplal1, Lyrm4, Maoa, Maob, Mcat, Mccc1, Mccc2, Mcee, Mdh2, Me2, Me3, Mecr, Mgst1, Mgst3, Mlycd, Mmaa, Mmab, Mmadhc, Mmut, Mocs1, Mpc1, Mpc2, Mpst, Mrps36, Msra, Msrb2, Msrb3, mt-Co1, mt-Cytb, Mtarc1, Mtarc2, Mtfmt, Mthfd1l, Mthfd2, Mthfd2l, Mthfs, Mthfsl, Mto1, Nadk2, Nags, Nat8l, Naxd, Naxe, Ndufab1, Ndufs1, Ndufs2, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Neu4, Nfs1, Nfu1, Nit1, Nit2, Nme3, Nme4, Nme6, Nmnat3, Nnt, Noct, Nt5dc2, Nt5m, Nthl1, Nubpl, Nudt13, Nudt19, Nudt2, Nudt5, Nudt8, Nudt9, Oat, Ogdh, Ogdhl, Osbpl1a, Otc, Oxct1, Oxct2a, Oxr1, Oxsm, Paics, Pank2, Pcbd2, Pcca, Pccb, Pck2, Pcx, Pdha1, Pdha2, Pdhb, Pdhx, Pdk1, Pdk2, Pdk3, Pdk4, Pdp1, Pdp2, Pdpr, Pdss1, Pdss2, Pgs1, Phyh, Pisd, Pld6, Plpbp, Plscr3, Pnpla8, Pnpo, Ppa2, Ppm1k, Ppox, Prdx2, Prdx3, Prdx4, Prdx5, Prdx6, Prelid1, Prelid3a, Prelid3b, Prodh, Prodh2, Prxl2a, Ptges2, Ptpmt1, Pycr1, Pycr2, Qdpr, Rdh13, Rdh14, Rfk, Rpia, Rsad1, Sardh, Sco1, Sco2, Scp2, Sdha, Sdhb, Sdhc, Sdhd, Sdsl, Selenoo, Serac1, Sfxn1, Sfxn3, Sfxn5, Shmt2, Sirt3, Sirt4, Sirt5, Slc25a1, Slc25a10, Slc25a11, Slc25a12, Slc25a13, Slc25a14, Slc25a15, Slc25a19, Slc25a2, Slc25a20, Slc25a21, Slc25a23, Slc25a24, Slc25a25, Slc25a28, Slc25a29, Slc25a3, Slc25a30, Slc25a31, Slc25a32, Slc25a33, Slc25a36, Slc25a37, Slc25a38, Slc25a4, Slc25a41, Slc25a42, Slc25a44, Slc25a5, Slc25a51, Sod1, Sod2, Sphk2, Spr, Sptlc2, Sqor, Star, Stard7, Sucla2, Suclg1, Suclg2, Sugct, Suox, Tamm41, Taz, Them4, Them5, Tk2, Tmlhe, Triap1, Tspo, Tst, Tstd1, Txn2, Txnrd1, Txnrd2, Uqcrfs1, Zadh2	464	Metabolism
57	Carbohydrate metabolism	Metabolism > Carbohydrate metabolism	Abhd11, Acaa2, Acat1, Acly, Aco2, Acod1, Auh, Bdh1, Clybl, Cs, D2hgdh, Dcxr, Dlat, Dld, Dlst, Fahd1, Fh1, Glyctk, Gm4984, Got2, Gpd2, Hadhb, Hmgcl, Hmgcs2, Idh2, Idh3a, Idh3b, Idh3g, L2hgdh, Ldhal6b, Ldhd, Mcee, Mdh2, Me2, Me3, Mmut, Mpc1, Mpc2, Mrps36, Neu4, Ogdh, Ogdhl, Oxct1, Oxct2a, Pcca, Pccb, Pck2, Pcx, Pdha1, Pdha2, Pdhb, Pdhx, Pdk1, Pdk2, Pdk3, Pdk4, Pdp1, Pdp2, Pdpr, Rpia, Sdha, Sdhb, Sdhc, Sdhd, Sfxn5, Slc25a1, Slc25a10, Slc25a11, Slc25a12, Slc25a13, Sucla2, Suclg1, Suclg2	73	Metabolism	Carbohydrate metabolism
58	Gluconeogenesis	Metabolism > Carbohydrate metabolism > Gluconeogenesis	Gm4984, Mdh2, Mpc1, Mpc2, Pck2, Pcx, Slc25a1, Slc25a10, Slc25a11	9	Metabolism	Carbohydrate metabolism	Gluconeogenesis
59	Malate-aspartate shuttle	Metabolism > Carbohydrate metabolism > Malate-aspartate shuttle	Got2, Mdh2, Slc25a10, Slc25a11, Slc25a12, Slc25a13	6	Metabolism	Carbohydrate metabolism	Malate-aspartate shuttle
60	Glycerol phosphate shuttle	Metabolism > Carbohydrate metabolism > Glycerol phosphate shuttle	Gpd2	1	Metabolism	Carbohydrate metabolism	Glycerol phosphate shuttle
61	Pyruvate metabolism	Metabolism > Carbohydrate metabolism > Pyruvate metabolism	Dlat, Dld, Gm4984, Mpc1, Mpc2, Pdha1, Pdha2, Pdhb, Pdhx, Pdk1, Pdk2, Pdk3, Pdk4, Pdp1, Pdp2, Pdpr	16	Metabolism	Carbohydrate metabolism	Pyruvate metabolism
62	TCA cycle	Metabolism > Carbohydrate metabolism > TCA cycle	Aco2, Cs, Dld, Dlst, Fh1, Idh2, Idh3a, Idh3b, Idh3g, Mdh2, Mrps36, Ogdh, Ogdhl, Sdha, Sdhb, Sdhc, Sdhd, Sucla2, Suclg1, Suclg2	20	Metabolism	Carbohydrate metabolism	TCA cycle
63	TCA-associated	Metabolism > Carbohydrate metabolism > TCA-associated	Abhd11, Acly, D2hgdh, Fahd1, Gm4984, L2hgdh, Me2, Me3, Mpc1, Mpc2, Pck2, Pcx, Sfxn5, Slc25a1, Slc25a11	15	Metabolism	Carbohydrate metabolism	TCA-associated
64	Itaconate metabolism	Metabolism > Carbohydrate metabolism > Itaconate metabolism	Acod1, Auh, Clybl, Sucla2, Suclg1, Suclg2	6	Metabolism	Carbohydrate metabolism	Itaconate metabolism
65	Ketone metabolism	Metabolism > Carbohydrate metabolism > Ketone metabolism	Acaa2, Acat1, Bdh1, Hadhb, Hmgcl, Hmgcs2, Oxct1, Oxct2a	8	Metabolism	Carbohydrate metabolism	Ketone metabolism
66	Propanoate metabolism	Metabolism > Carbohydrate metabolism > Propanoate metabolism	Mcee, Mmut, Pcca, Pccb	4	Metabolism	Carbohydrate metabolism	Propanoate metabolism
67	Lipid metabolism	Metabolism > Lipid metabolism	Acaa1a, Acaa1b, Acaa2, Acaca, Acacb, Acad10, Acad11, Acad12, Acadl, Acadm, Acads, Acadsb, Acadvl, Acat1, Acot10, Acot11, Acot13, Acot2, Acot7, Acot9, Acp6, Acsf2, Acsf3, Acsl1, Acsl6, Acsm1, Acsm2, Acsm3, Acsm4, Acsm5, Acss1, Acss3, Agk, Agpat4, Agpat5, Akr1b7, Amacr, Cbr4, Chpt1, Cpt1a, Cpt1b, Cpt1c, Cpt2, Crat, Crls1, Crot, Cyb5r3, Cyp11a1, Cyp11b1, Cyp11b2, Cyp27a1, Dbi, Decr1, Dhrs1, Ech1, Echdc1, Echs1, Eci1, Eci2, Ehhadh, Ephx2, Etfa, Etfb, Etfdh, Fabp1, Fasn, Fdps, Fdx1, Fdxr, Gcsh, Gpam, Gpat2, H2-Ke6, Hadh, Hadha, Hadhb, Hao2, Hint2, Hsd17b10, Hsd17b4, Htd2, Idi1, Lactb, Lias, Lipt1, Lipt2, Lypla1, Lyplal1, Mcat, Mcee, Mecr, Mgst3, Mlycd, Mmut, Ndufab1, Osbpl1a, Oxsm, Pcca, Pccb, Pgs1, Phyh, Pisd, Pld6, Plscr3, Pnpla8, Prdx6, Prelid1, Prelid3a, Prelid3b, Ptges2, Ptpmt1, Scp2, Serac1, Slc25a1, Slc25a20, Sphk2, Sptlc2, Star, Stard7, Tamm41, Taz, Them4, Them5, Triap1, Tspo, Zadh2	126	Metabolism	Lipid metabolism
68	Fatty acid oxidation	Metabolism > Lipid metabolism > Fatty acid oxidation	Acaa1a, Acaa2, Acacb, Acad10, Acad11, Acad12, Acadl, Acadm, Acads, Acadsb, Acadvl, Acat1, Acot11, Acsf2, Acsl1, Acsl6, Acsm1, Acsm2, Acsm3, Acsm4, Acsm5, Acss1, Amacr, Cpt1a, Cpt1b, Cpt1c, Cpt2, Crat, Crot, Decr1, Echs1, Eci1, Eci2, Etfa, Etfb, Etfdh, Hadh, Hadha, Hadhb, Hsd17b10, Mcee, Mmut, Pcca, Pccb, Slc25a20	45	Metabolism	Lipid metabolism	Fatty acid oxidation
69	Type II fatty acid synthesis	Metabolism > Lipid metabolism > Type II fatty acid synthesis	Acaca, Acsf3, Cbr4, H2-Ke6, Htd2, Mcat, Mecr, Ndufab1, Oxsm	9	Metabolism	Lipid metabolism	Type II fatty acid synthesis
70	Lipoate insertion	Metabolism > Lipid metabolism > Lipoate insertion	Gcsh, Lias, Lipt1, Lipt2	4	Metabolism	Lipid metabolism	Lipoate insertion
71	Cardiolipin synthesis	Metabolism > Lipid metabolism > Cardiolipin synthesis	Agpat4, Agpat5, Crls1, Gpam, Gpat2, Hadha, Pgs1, Pld6, Plscr3, Pnpla8, Prelid1, Prelid3a, Ptpmt1, Tamm41, Taz, Triap1	16	Metabolism	Lipid metabolism	Cardiolipin synthesis
72	Cholesterol, bile acid, steroid synthesis	Metabolism > Lipid metabolism > Cholesterol, bile acid, steroid synthesis	Cyp11a1, Cyp11b1, Cyp11b2, Cyp27a1, Dhrs1, Fdx1, Fdxr, H2-Ke6, Hint2, Hsd17b10, Osbpl1a, Scp2, Star, Tspo	14	Metabolism	Lipid metabolism	Cholesterol, bile acid, steroid synthesis
73	Cholesterol-associated	Metabolism > Lipid metabolism > Cholesterol-associated	Fdps, Idi1	2	Metabolism	Lipid metabolism	Cholesterol-associated
74	Phospholipid metabolism	Metabolism > Lipid metabolism > Phospholipid metabolism	Acp6, Agk, Agpat4, Agpat5, Akr1b7, Chpt1, Gpam, Gpat2, Lactb, Osbpl1a, Pgs1, Pisd, Pnpla8, Prdx6, Prelid1, Prelid3a, Prelid3b, Ptpmt1, Serac1, Sphk2, Sptlc2, Stard7, Tamm41, Triap1	24	Metabolism	Lipid metabolism	Phospholipid metabolism
75	Eicosanoid metabolism	Metabolism > Lipid metabolism > Eicosanoid metabolism	Mgst3, Ptges2, Zadh2	3	Metabolism	Lipid metabolism	Eicosanoid metabolism
76	Amino acid metabolism	Metabolism > Amino acid metabolism	Aadat, Aass, Abat, Acaa2, Acad8, Acadsb, Acat1, Adhfe1, Agmat, Agxt, Agxt2, Akr7a5, Aldh18a1, Aldh4a1, Aldh5a1, Aldh6a1, Aldh7a1, Aldh9a1, Amt, Arg2, Auh, Bcat2, Bckdha, Bckdhb, Bckdk, Car5a, Car5b, Chdh, Comt, Cps1, Dbt, Dglucy, Dhtkd1, Dld, Dlst, Dmgdh, Echs1, Etfa, Etfb, Etfdh, Gcat, Gcdh, Gcsh, Gldc, Gls, Gls2, Glud1, Glyat, Got2, Gpt2, Grhpr, Hadh, Hadha, Hadhb, Hibadh, Hibch, Hmgcl, Hoga1, Hsd17b10, Ivd, Kmo, Kyat3, Ldhb, Maoa, Maob, Mccc1, Mccc2, Nags, Nat8l, Oat, Otc, Ppm1k, Prodh, Prodh2, Pycr1, Pycr2, Sardh, Sdsl, Sfxn1, Sfxn3, Shmt2, Slc25a12, Slc25a13, Slc25a15, Slc25a2, Slc25a21, Slc25a29, Slc25a38, Slc25a44, Sugct	90	Metabolism	Amino acid metabolism
77	Branched-chain amino acid metabolism	Metabolism > Amino acid metabolism > Branched-chain amino acid metabolism	Acad8, Acadsb, Acat1, Aldh6a1, Auh, Bcat2, Bckdha, Bckdhb, Bckdk, Dbt, Dld, Echs1, Etfa, Etfb, Etfdh, Hadha, Hibadh, Hibch, Hmgcl, Hsd17b10, Ivd, Mccc1, Mccc2, Ppm1k, Slc25a44	25	Metabolism	Amino acid metabolism	Branched-chain amino acid metabolism
78	Branched-chain amino acid dehydrogenase complex	Metabolism > Amino acid metabolism > Branched-chain amino acid dehydrogenase complex	Bckdha, Bckdhb, Bckdk, Dbt, Dld, Ppm1k	6	Metabolism	Amino acid metabolism	Branched-chain amino acid dehydrogenase complex
79	Lysine metabolism	Metabolism > Amino acid metabolism > Lysine metabolism	Aadat, Aass, Acaa2, Acat1, Aldh7a1, Dhtkd1, Dld, Dlst, Echs1, Etfa, Etfb, Etfdh, Gcdh, Hadh, Hadhb, Slc25a29	16	Metabolism	Amino acid metabolism	Lysine metabolism
80	Serine metabolism	Metabolism > Amino acid metabolism > Serine metabolism	Agxt, Sdsl, Sfxn1, Sfxn3, Shmt2	5	Metabolism	Amino acid metabolism	Serine metabolism
81	Glycine metabolism	Metabolism > Amino acid metabolism > Glycine metabolism	Aldh7a1, Amt, Chdh, Dld, Dmgdh, Etfa, Etfb, Etfdh, Gcat, Gcsh, Gldc, Glyat, Sardh, Shmt2, Slc25a38	15	Metabolism	Amino acid metabolism	Glycine metabolism
82	Glycine cleavage system	Metabolism > Amino acid metabolism > Glycine cleavage system	Amt, Dld, Gcsh, Gldc	4	Metabolism	Amino acid metabolism	Glycine cleavage system
83	Glutamate metabolism	Metabolism > Amino acid metabolism > Glutamate metabolism	Gls, Gls2, Glud1, Got2, Gpt2, Nat8l, Slc25a12	7	Metabolism	Amino acid metabolism	Glutamate metabolism
84	Proline metabolism	Metabolism > Amino acid metabolism > Proline metabolism	Aldh18a1, Aldh4a1, Oat, Prodh, Pycr1, Pycr2	6	Metabolism	Amino acid metabolism	Proline metabolism
85	Glyoxylate metabolism	Metabolism > Amino acid metabolism > Glyoxylate metabolism	Agxt, Agxt2, Aldh4a1, Got2, Grhpr, Hoga1, Ldhb, Prodh2	8	Metabolism	Amino acid metabolism	Glyoxylate metabolism
86	GABA metabolism	Metabolism > Amino acid metabolism > GABA metabolism	Abat, Adhfe1, Akr7a5, Aldh5a1, Aldh9a1, Glud1	6	Metabolism	Amino acid metabolism	GABA metabolism
87	Catechol metabolism	Metabolism > Amino acid metabolism > Catechol metabolism	Comt, Maoa, Maob	3	Metabolism	Amino acid metabolism	Catechol metabolism
88	Kynurenine metabolism	Metabolism > Amino acid metabolism > Kynurenine metabolism	Got2, Kmo, Kyat3	3	Metabolism	Amino acid metabolism	Kynurenine metabolism
89	Urea cycle	Metabolism > Amino acid metabolism > Urea cycle	Car5a, Car5b, Cps1, Nags, Otc, Slc25a13, Slc25a15, Slc25a2	8	Metabolism	Amino acid metabolism	Urea cycle
90	Nucleotide metabolism	Metabolism > Nucleotide metabolism	Ak2, Ak3, Ak4, Antkmt, Ckmt1, Ckmt2, Cmpk2, Dguok, Dhodh, Dut, Fhit, Gatm, Guk1, Hint1, Nme3, Nme4, Nme6, Nt5dc2, Nt5m, Nudt2, Nudt5, Nudt9, Paics, Ppa2, Slc25a23, Slc25a24, Slc25a25, Slc25a31, Slc25a33, Slc25a36, Slc25a4, Slc25a41, Slc25a5, Sucla2, Suclg1, Tk2	36	Metabolism	Nucleotide metabolism
91	Nucleotide import	Metabolism > Nucleotide metabolism > Nucleotide import	Slc25a23, Slc25a24, Slc25a25, Slc25a31, Slc25a33, Slc25a36, Slc25a4, Slc25a41, Slc25a5	9	Metabolism	Nucleotide metabolism	Nucleotide import
92	Nucleotide synthesis and processing	Metabolism > Nucleotide metabolism > Nucleotide synthesis and processing	Ak2, Ak3, Ak4, Cmpk2, Dguok, Dhodh, Dut, Fhit, Guk1, Hint1, Nme3, Nme4, Nme6, Nt5dc2, Nt5m, Nudt2, Nudt5, Nudt9, Paics, Sucla2, Suclg1, Tk2	22	Metabolism	Nucleotide metabolism	Nucleotide synthesis and processing
93	Creatine metabolism	Metabolism > Nucleotide metabolism > Creatine metabolism	Ckmt1, Ckmt2, Gatm	3	Metabolism	Nucleotide metabolism	Creatine metabolism
94	Metals and cofactors	Metabolism > Metals and cofactors	Abat, Abcb10, Abcb6, Abcb7, Aco2, Aifm3, Alas1, Alas2, Bola1, Bola3, Chchd7, Cisd1, Cisd3, Coasy, Coq10a, Coq10b, Coq2, Coq3, Coq4, Coq5, Coq6, Coq7, Coq8a, Coq8b, Coq9, Cox10, Cox11, Cox15, Cox17, Cox19, Cpox, Cpt1a, Cpt1b, Cpt1c, Cpt2, Cyb5b, Cyc1, Cycs, Cyp11a1, Cyp11b2, Cyp24a1, Cyp27a1, Cyp27b1, Dna2, Etfdh, Fabp1, Fam210b, Fdx1, Fdx2, Fdxr, Fech, Fth1, Ftmt, Fxn, Glrx2, Glrx5, Grpel1, Grpel2, Hccs, Hscb, Hspa9, Iba57, Isca1, Isca2, Iscu, Kmo, Kyat3, Lias, Lyrm4, Mocs1, mt-Co1, mt-Cytb, Mtarc1, Mtarc2, Nadk2, Naxd, Naxe, Ndufab1, Ndufs1, Ndufs2, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Nfs1, Nfu1, Nmnat3, Nnt, Noct, Nthl1, Nubpl, Nudt13, Nudt19, Nudt8, Pank2, Pcbd2, Pdss1, Pdss2, Ppox, Qdpr, Rsad1, Sco1, Sco2, Sdhb, Sdhc, Sdhd, Sirt3, Sirt4, Sirt5, Slc25a20, Slc25a28, Slc25a3, Slc25a37, Slc25a38, Slc25a42, Slc25a51, Spr, Suox, Tmlhe, Uqcrfs1	120	Metabolism	Metals and cofactors
95	Carnitine synthesis and transport	Metabolism > Metals and cofactors > Carnitine synthesis and transport	Cpt1a, Cpt1b, Cpt1c, Cpt2, Slc25a20, Tmlhe	6	Metabolism	Metals and cofactors	Carnitine synthesis and transport
96	Carnitine shuttle	Metabolism > Metals and cofactors > Carnitine shuttle	Cpt1a, Cpt1b, Cpt1c, Cpt2, Slc25a20	5	Metabolism	Metals and cofactors	Carnitine shuttle
97	Coenzyme A metabolism	Metabolism > Metals and cofactors > Coenzyme A metabolism	Coasy, Nudt19, Nudt8, Pank2, Slc25a42	5	Metabolism	Metals and cofactors	Coenzyme A metabolism
98	Coenzyme Q metabolism	Metabolism > Metals and cofactors > Coenzyme Q metabolism	Coq10a, Coq10b, Coq2, Coq3, Coq4, Coq5, Coq6, Coq7, Coq8a, Coq8b, Coq9, Pdss1, Pdss2	13	Metabolism	Metals and cofactors	Coenzyme Q metabolism
99	Copper metabolism	Metabolism > Metals and cofactors > Copper metabolism	Chchd7, Cox11, Cox17, Cox19, Sco1, Sco2, Slc25a3	7	Metabolism	Metals and cofactors	Copper metabolism
100	Iron homeostasis	Metabolism > Metals and cofactors > Iron homeostasis	Fam210b, Fth1, Ftmt, Slc25a28, Slc25a37	5	Metabolism	Metals and cofactors	Iron homeostasis
101	Heme synthesis and processing	Metabolism > Metals and cofactors > Heme synthesis and processing	Abcb10, Abcb6, Abcb7, Alas1, Alas2, Cox10, Cox15, Cpox, Fabp1, Fdx1, Fdx2, Fdxr, Fech, Hccs, Ppox, Slc25a38	16	Metabolism	Metals and cofactors	Heme synthesis and processing
102	Fe-S cluster biosynthesis	Metabolism > Metals and cofactors > Fe-S cluster biosynthesis	Abcb7, Bola1, Bola3, Cisd1, Cisd3, Fdx1, Fdx2, Fdxr, Fxn, Glrx5, Grpel1, Grpel2, Hscb, Hspa9, Iba57, Isca1, Isca2, Iscu, Lyrm4, Ndufab1, Nfs1, Nfu1, Nubpl	23	Metabolism	Metals and cofactors	Fe-S cluster biosynthesis
103	Molybdenum cofactor synthesis and proteins	Metabolism > Metals and cofactors > Molybdenum cofactor synthesis and proteins	Abcb7, Mocs1, Mtarc1, Mtarc2, Suox	5	Metabolism	Metals and cofactors	Molybdenum cofactor synthesis and proteins
104	NAD biosynthesis and metabolism	Metabolism > Metals and cofactors > NAD biosynthesis and metabolism	Kmo, Kyat3, Nadk2, Naxd, Naxe, Nmnat3, Nnt, Noct, Nudt13, Sirt3, Sirt4, Sirt5, Slc25a51	13	Metabolism	Metals and cofactors	NAD biosynthesis and metabolism
105	Tetrahydrobiopterin synthesis	Metabolism > Metals and cofactors > Tetrahydrobiopterin synthesis	Pcbd2, Qdpr, Spr	3	Metabolism	Metals and cofactors	Tetrahydrobiopterin synthesis
106	Fe-S-containing proteins	Metabolism > Metals and cofactors > Fe-S-containing proteins	Abat, Aco2, Aifm3, Bola1, Bola3, Cisd1, Cisd3, Dna2, Etfdh, Fdx1, Fdx2, Fech, Glrx2, Glrx5, Isca1, Isca2, Iscu, Lias, Ndufs1, Ndufs2, Ndufs7, Ndufs8, Ndufv1, Ndufv2, Nfs1, Nfu1, Nthl1, Nubpl, Rsad1, Sdhb, Uqcrfs1	31	Metabolism	Metals and cofactors	Fe-S-containing proteins
107	Heme-containing proteins	Metabolism > Metals and cofactors > Heme-containing proteins	Cyb5b, Cyc1, Cycs, Cyp11a1, Cyp11b2, Cyp24a1, Cyp27a1, Cyp27b1, mt-Co1, mt-Cytb, Sdhc, Sdhd	12	Metabolism	Metals and cofactors	Heme-containing proteins
108	Vitamin metabolism	Metabolism > Vitamin metabolism	Acaca, Acacb, Akr1b10, Aldh1l1, Aldh1l2, Aldh7a1, Amt, Bco2, Chdh, Cyp24a1, Cyp27b1, Dhrs4, Dmgdh, Etfa, Etfb, Etfdh, Fdx1, Fdxr, Flad1, Fpgs, Glrx2, Gtpbp3, Mccc1, Mmaa, Mmab, Mmadhc, Mmut, Mtfmt, Mthfd1l, Mthfd2, Mthfd2l, Mthfs, Mthfsl, Mto1, Pcca, Pcx, Plpbp, Pnpo, Qdpr, Rdh13, Rdh14, Rfk, Sardh, Sfxn1, Sfxn3, Shmt2, Slc25a19, Slc25a32, Slc25a38, Txn2	50	Metabolism	Vitamin metabolism
109	Choline and betaine metabolism	Metabolism > Vitamin metabolism > Choline and betaine metabolism	Aldh7a1, Chdh, Dmgdh, Etfa, Etfb, Etfdh, Sardh	7	Metabolism	Vitamin metabolism	Choline and betaine metabolism
110	Biotin utilizing proteins	Metabolism > Vitamin metabolism > Biotin utilizing proteins	Acaca, Acacb, Mccc1, Pcca, Pcx	5	Metabolism	Vitamin metabolism	Biotin utilizing proteins
111	Vitamin A metabolism	Metabolism > Vitamin metabolism > Vitamin A metabolism	Akr1b10, Bco2, Dhrs4, Rdh13, Rdh14	5	Metabolism	Vitamin metabolism	Vitamin A metabolism
112	Vitamin B1 metabolism	Metabolism > Vitamin metabolism > Vitamin B1 metabolism	Slc25a19	1	Metabolism	Vitamin metabolism	Vitamin B1 metabolism
113	Vitamin B2 metabolism	Metabolism > Vitamin metabolism > Vitamin B2 metabolism	Flad1, Rfk, Slc25a32	3	Metabolism	Vitamin metabolism	Vitamin B2 metabolism
114	Vitamin B6 metabolism	Metabolism > Vitamin metabolism > Vitamin B6 metabolism	Plpbp, Pnpo	2	Metabolism	Vitamin metabolism	Vitamin B6 metabolism
115	Vitamin B12 metabolism	Metabolism > Vitamin metabolism > Vitamin B12 metabolism	Mmaa, Mmab, Mmadhc, Mmut	4	Metabolism	Vitamin metabolism	Vitamin B12 metabolism
116	Vitamin C metabolism	Metabolism > Vitamin metabolism > Vitamin C metabolism	Glrx2, Txn2	2	Metabolism	Vitamin metabolism	Vitamin C metabolism
117	Vitamin D metabolism	Metabolism > Vitamin metabolism > Vitamin D metabolism	Cyp24a1, Cyp27b1, Fdx1, Fdxr	4	Metabolism	Vitamin metabolism	Vitamin D metabolism
118	Folate and 1-C metabolism	Metabolism > Vitamin metabolism > Folate and 1-C metabolism	Aldh1l1, Aldh1l2, Aldh7a1, Amt, Chdh, Dmgdh, Fpgs, Gtpbp3, Mtfmt, Mthfd1l, Mthfd2, Mthfd2l, Mthfs, Mthfsl, Mto1, Qdpr, Sardh, Sfxn1, Sfxn3, Shmt2, Slc25a32, Slc25a38	22	Metabolism	Vitamin metabolism	Folate and 1-C metabolism
119	Detoxification	Metabolism > Detoxification	Abhd10, Acsm2, Acsm5, Aifm2, Akr1b10, Akr7a5, Aldh1b1, Aldh2, Aldh3a2, Aldh7a1, Aldh9a1, Bphl, Cat, Cbr3, Cyb5b, Cyb5r3, Dhrs2, Ephx2, Glrx2, Glyat, Gpx1, Gpx4, Gsr, Gstk1, Gstz1, Hagh, Maoa, Maob, Mgst1, Mpst, Msra, Msrb2, Msrb3, Mtarc1, Mtarc2, Nit1, Nit2, Oxr1, Prdx2, Prdx3, Prdx4, Prdx5, Prdx6, Prxl2a, Selenoo, Sod1, Sod2, Tst, Txn2, Txnrd1, Txnrd2	51	Metabolism	Detoxification
120	Xenobiotic metabolism	Metabolism > Detoxification > Xenobiotic metabolism	Abhd10, Acsm2, Acsm5, Akr1b10, Akr7a5, Aldh1b1, Aldh2, Bphl, Cbr3, Cyb5b, Cyb5r3, Dhrs2, Ephx2, Glyat, Gstk1, Gstz1, Maoa, Maob, Mgst1, Mpst, Mtarc1, Mtarc2, Tst	23	Metabolism	Detoxification	Xenobiotic metabolism
121	ROS and glutathione metabolism	Metabolism > Detoxification > ROS and glutathione metabolism	Aifm2, Aldh3a2, Aldh7a1, Aldh9a1, Cat, Glrx2, Gpx1, Gpx4, Gsr, Hagh, Mgst1, Msra, Msrb2, Msrb3, Nit1, Oxr1, Prdx2, Prdx3, Prdx4, Prdx5, Prdx6, Prxl2a, Sod1, Sod2, Txn2, Txnrd1, Txnrd2	27	Metabolism	Detoxification	ROS and glutathione metabolism
122	Amidoxime reducing complex	Metabolism > Detoxification > Amidoxime reducing complex	Cyb5b, Cyb5r3, Mtarc1, Mtarc2	4	Metabolism	Detoxification	Amidoxime reducing complex
123	Selenoproteins	Metabolism > Detoxification > Selenoproteins	Gpx1, Gpx4, Selenoo, Txnrd1, Txnrd2	5	Metabolism	Detoxification	Selenoproteins
124	Electron carriers	Metabolism > Electron carriers	Chdh, Cyb5b, Cyc1, Cycs, Cyct, Dhodh, Etfa, Etfb, Etfbkmt, Etfdh, Etfrf1, Gpd2, mt-Cytb, Prodh, Prodh2, Sqor	16	Metabolism	Electron carriers
125	Cytochromes	Metabolism > Electron carriers > Cytochromes	Cyb5b, Cyc1, Cycs, Cyct, mt-Cytb	5	Metabolism	Electron carriers	Cytochromes
126	Q-linked reactions, other	Metabolism > Electron carriers > Q-linked reactions, other	Chdh, Dhodh, Etfa, Etfb, Etfbkmt, Etfdh, Etfrf1, Gpd2, Prodh, Prodh2, Sqor	11	Metabolism	Electron carriers	Q-linked reactions, other
127	Sulfur metabolism	Metabolism > Sulfur metabolism	Ethe1, Got2, Mpst, Msra, Msrb2, Slc25a14, Slc25a30, Sqor, Suox, Tst, Tstd1	11	Metabolism	Sulfur metabolism
128	Small molecule transport	Small molecule transport	Abca9, Abcb10, Abcb6, Abcb7, Abcb8, Abcd1, Abcd2, Abcd3, Ccdc51, Gm4984, Letmd1, Mcu, Mcub, Micu1, Micu2, Micu3, Mpc1, Mpc2, Mpv17, Mpv17l, Mrs2, Mtch1, Mtch2, Romo1, Sfxn1, Sfxn2, Sfxn3, Sfxn4, Sfxn5, Slc25a1, Slc25a10, Slc25a11, Slc25a12, Slc25a13, Slc25a14, Slc25a15, Slc25a16, Slc25a18, Slc25a19, Slc25a2, Slc25a20, Slc25a21, Slc25a22, Slc25a23, Slc25a24, Slc25a25, Slc25a26, Slc25a27, Slc25a28, Slc25a29, Slc25a3, Slc25a30, Slc25a31, Slc25a32, Slc25a33, Slc25a34, Slc25a35, Slc25a36, Slc25a37, Slc25a38, Slc25a39, Slc25a4, Slc25a40, Slc25a41, Slc25a42, Slc25a43, Slc25a44, Slc25a45, Slc25a46, Slc25a47, Slc25a48, Slc25a5, Slc25a51, Slc25a53, Slc25a54, Slc30a9, Slc8b1, Smdt1, Stard7, Ucp1, Ucp2, Ucp3, Vdac1, Vdac2, Vdac3	85	Small molecule transport
129	SLC25A family	Small molecule transport > SLC25A family	Mtch1, Mtch2, Slc25a1, Slc25a10, Slc25a11, Slc25a12, Slc25a13, Slc25a14, Slc25a15, Slc25a16, Slc25a18, Slc25a19, Slc25a2, Slc25a20, Slc25a21, Slc25a22, Slc25a23, Slc25a24, Slc25a25, Slc25a26, Slc25a27, Slc25a28, Slc25a29, Slc25a3, Slc25a30, Slc25a31, Slc25a32, Slc25a33, Slc25a34, Slc25a35, Slc25a36, Slc25a37, Slc25a38, Slc25a39, Slc25a4, Slc25a40, Slc25a41, Slc25a42, Slc25a43, Slc25a44, Slc25a45, Slc25a46, Slc25a47, Slc25a48, Slc25a5, Slc25a51, Slc25a53, Slc25a54, Ucp1, Ucp2, Ucp3	51	Small molecule transport	SLC25A family
130	ABC transporters	Small molecule transport > ABC transporters	Abca9, Abcb10, Abcb6, Abcb7, Abcb8, Abcd1, Abcd2, Abcd3	8	Small molecule transport	ABC transporters
131	Sideroflexins	Small molecule transport > Sideroflexins	Sfxn1, Sfxn2, Sfxn3, Sfxn4, Sfxn5	5	Small molecule transport	Sideroflexins
132	Signaling	Signaling	Acod1, Adcy10, Akap1, Akap10, Bloc1s1, C1qbp, Cstad, Dele1, Efhd1, Fundc2, Ifi27, Letm1, Lypla1, Macrod1, Mavs, Mcrip2, Mcu, Mcub, Micu1, Micu2, Micu3, Mrs2, Mul1, Nlrx1, Ociad2, Pde2a, Pink1, Ppif, Pptc7, Prkaca, Rhot1, Rhot2, Sirt3, Slc25a12, Slc25a13, Slc25a23, Slc25a24, Slc25a25, Slc25a3, Slc25a31, Slc25a4, Slc25a5, Slc8b1, Smdt1, Sphkap, Vdac1, Vdac3	47	Signaling
133	Calcium homeostasis	Signaling > Calcium homeostasis	Efhd1, Letm1, Mcu, Mcub, Micu1, Micu2, Micu3, Ppif, Rhot1, Rhot2, Slc25a12, Slc25a13, Slc25a23, Slc25a24, Slc25a25, Slc25a3, Slc25a31, Slc25a4, Slc25a5, Slc8b1, Smdt1, Vdac1, Vdac3	23	Signaling	Calcium homeostasis
134	Calcium uniporter	Small molecule transport > Calcium uniporter	Mcu, Mcub, Micu1, Micu2, Micu3, Smdt1	6	Small molecule transport	Calcium uniporter
135	Calcium cycle	Signaling > Calcium homeostasis > Calcium cycle	Letm1, Mcu, Mcub, Micu1, Micu2, Micu3, Slc25a3, Slc8b1, Smdt1	9	Signaling	Calcium homeostasis	Calcium cycle
136	Mitochondrial permeability transition pore	Signaling > Calcium homeostasis > Mitochondrial permeability transition pore	Ppif, Slc25a31, Slc25a4, Slc25a5, Vdac1, Vdac3	6	Signaling	Calcium homeostasis	Mitochondrial permeability transition pore
137	EF hand proteins	Signaling > Calcium homeostasis > EF hand proteins	Efhd1, Micu1, Micu2, Micu3, Rhot1, Rhot2, Slc25a12, Slc25a13, Slc25a23, Slc25a24, Slc25a25	11	Signaling	Calcium homeostasis	EF hand proteins
138	Immune response	Signaling > Immune response	Acod1, C1qbp, Cstad, Ifi27, Mavs, Nlrx1	6	Signaling	Immune response
139	cAMP-PKA signaling	Signaling > cAMP-PKA signaling	Adcy10, Akap1, Akap10, Pde2a, Prkaca, Sphkap	6	Signaling	cAMP-PKA signaling
140	Mitochondrial dynamics and surveillance	Mitochondrial dynamics and surveillance	Ahcyl1, Aifm1, Aifm2, Aifm3, Apoo, Apool, Arl2, Armc10, Armcx1, Armcx3, Atad3a, Atp5k, Atp5l, Atp5md, Bad, Bak1, Bax, Bbc3, Bcl2, Bcl2a1d, Bcl2l1, Bcl2l10, Bcl2l11, Bcl2l13, Bcl2l2, Bid, Bik, Bnip3, Bnip3l, Bok, Casp3, Casp8, Casp9, Chchd2, Chchd3, Chchd6, Cycs, Diablo, Dnajc11, Dnm1l, Endog, Fis1, Fkbp8, Fundc1, Fundc2, Ghitm, Htra2, Ifi27, Immt, Marchf5, Mcl1, Mff, Mfn1, Mfn2, Mgarp, Micos10, Micos13, Mief1, Mief2, Miga1, Miga2, Mtch2, Mtfp1, Mtfr1, Mtfr2, Mtx1, Mtx2, Mtx3, Mul1, Myo19, Nbr1, Nipsnap1, Nipsnap2, Oma1, Opa1, Park7, Parl, Pgam5, Pigbos1, Pink1, Pld6, Pmaip1, Prkn, Rab24, Rhot1, Rhot2, Rmdn3, Samm50, Septin4, Slc25a46, Snap29, Sphk2, Spire1, Stx17, Styxl1, Synj2bp, Tmem11, Tomm20, Tomm7, Usp30, Vdac1, Vps13d	102	Mitochondrial dynamics and surveillance
141	Fusion	Mitochondrial dynamics and surveillance > Fusion	Arl2, Mfn1, Mfn2, Miga1, Miga2, Mtch2, Oma1, Opa1, Pld6	9	Mitochondrial dynamics and surveillance	Fusion
142	Fission	Mitochondrial dynamics and surveillance > Fission	Armc10, Dnm1l, Fis1, Mff, Mief1, Mief2, Mtfp1, Mtfr1, Mtfr2, Mul1, Oma1, Rab24, Slc25a46, Spire1, Stx17	15	Mitochondrial dynamics and surveillance	Fission
143	Organelle contact sites	Mitochondrial dynamics and surveillance > Organelle contact sites	Ahcyl1, Atad3a, Fkbp8, Fundc2, Mfn1, Mfn2, Miga2, Pigbos1, Rmdn3, Spire1, Stx17, Synj2bp, Vdac1	13	Mitochondrial dynamics and surveillance	Organelle contact sites
144	Intramitochondrial membrane interactions	Mitochondrial dynamics and surveillance > Intramitochondrial membrane interactions	Atad3a, Chchd3, Dnajc11, Mtx1, Mtx2, Mtx3, Samm50, Slc25a46	8	Mitochondrial dynamics and surveillance	Intramitochondrial membrane interactions
145	Trafficking	Mitochondrial dynamics and surveillance > Trafficking	Armc10, Armcx1, Armcx3, Mgarp, Myo19, Rhot1, Rhot2	7	Mitochondrial dynamics and surveillance	Trafficking
146	Mitophagy	Mitochondrial dynamics and surveillance > Mitophagy	Bcl2l13, Fkbp8, Fundc1, Marchf5, Nipsnap1, Nipsnap2, Park7, Parl, Pgam5, Pink1, Prkn, Tomm7, Usp30, Vps13d	14	Mitochondrial dynamics and surveillance	Mitophagy
147	Autophagy	Mitochondrial dynamics and surveillance > Autophagy	Bcl2l13, Fkbp8, Fundc1, Marchf5, Nbr1, Nipsnap1, Nipsnap2, Park7, Parl, Pgam5, Pink1, Prkn, Rab24, Snap29, Stx17, Tomm7, Usp30, Vps13d	18	Mitochondrial dynamics and surveillance	Autophagy
148	Apoptosis	Mitochondrial dynamics and surveillance > Apoptosis	Aifm1, Aifm2, Aifm3, Bad, Bak1, Bax, Bbc3, Bcl2, Bcl2a1d, Bcl2l1, Bcl2l10, Bcl2l11, Bcl2l13, Bcl2l2, Bid, Bik, Bnip3, Bnip3l, Bok, Casp3, Casp8, Casp9, Chchd2, Cycs, Diablo, Endog, Ghitm, Htra2, Ifi27, Mcl1, Pmaip1, Septin4, Sphk2, Styxl1	34	Mitochondrial dynamics and surveillance	Apoptosis
149	Cristae formation	Mitochondrial dynamics and surveillance > Cristae formation	Apoo, Apool, Atp5k, Atp5l, Atp5md, Chchd3, Chchd6, Immt, Micos10, Micos13, Opa1	11	Mitochondrial dynamics and surveillance	Cristae formation
150	MICOS complex	Mitochondrial dynamics and surveillance > Cristae formation > MICOS complex	Apoo, Apool, Chchd3, Chchd6, Immt, Micos10, Micos13	7	Mitochondrial dynamics and surveillance	Cristae formation	MICOS complex